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Hyperspectral Imaging Applications in Pharmaceutical PAT

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The US Food and Drug Administration (FDA) continues to make progress under the Pharmaceutical Quality for the 21st Century Initiative so Continuous Manufacturing (CM) and enabling Process Analytical Technologies (PAT) gain growing acceptance across the pharmaceutical manufacturing landscape.

The last few years have seen commercial approvals granted to a number of small-molecule drugs. This paradigm shift in drug manufacturing helps advanced spectroscopic imaging techniques demonstrate their value as continuous quality assurance tools in wide variety of applications.

Because hyperspectral industrial and research systems can see with high spectral resolution, pharmaceutical manufacturers can monitor and inspect their products for quality in real time. Continuous feedback from hyperspectral data helps engineers to better understand how manufacturing parameters change under different conditions. In packaging and inspection operations real time hyperspectral data can help detect process anomalies and foreign objects.